Postdoctoral Researcher
University Health Network
Toronto, ON-
Number of positions available : 1
- Salary To be discussed
- Full time
- Published on August 12th, 2024
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Starting date : 1 position to fill as soon as possible
Description
The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute and the Michener Institute of Education. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of ground breaking firsts and a purpose of “Transforming lives and communities through excellence in care, discovery and learning”, the University Health Network (UHN), Canada’s largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.
Position Summary
A POSTDOCTORAL position is available in the laboratory of Professor Hakem at the Princess Margaret Cancer Centre/University Health Network, Toronto/Canada. https://medbio.utoronto.ca/faculty/hakem https://www.uhnresearch.ca/researcher/razqallah-hakem
Our lab is interested in characterizing novel cancer mechanisms and exploiting therapeutic vulnerabilities to kill aggressive cancers. https://orcid.org/0000-0001-5948-7931
Cancer genetics, DNA damage repair, genome-wide CRISPR-Cas9 screening, biochemistry, transcriptomics, epigenetics, chromatin remodeling, pharmacogenomics, and multi-omics integration are the pillars of our research program. For our studies, we use mouse models, Patients Derived Xenografts (PDXs), Patient Derived Organoids (PDOs), as well as publicly available cancer databases (e.g., TCGA). We work towards improving cancer patients' therapy by using systems biology, multidisciplinary approaches, and working with our collaborator’s scientists, clinicians, pathologists, medicinal chemists, and computational biologists”.
The Hakem lab has an excellent track record studying cancer mechanisms and related signaling pathways. Our studies have been published in excellent peer-reviewed journals including Science (doi.10.1126/science.1094557), Nature Communications (doi.10.1038/ncomms12638), the Journal of Clinical Investigation (doi. 10.1172/JCI140105 and doi.10.1172/JCI120401), Nucleic Acids Research (doi.10.1093/nar/gkad172 and doi.10.1093/nar/gkad733), and Nature Structural and Molecular Biology (doi.10.1038/s41594-024-01286-7).
Duties
In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.
UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.
Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.
UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.
We thank all applicants for their interest, however, only those selected for further consideration will be contacted.
Requirements
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